
姓名:毛春
职称:教授/博士生导师
学位学历:博士
E-mail: maochun@njnu.edu.cn
个人简历(Personal profile)
2004年6月毕业于南京大学化学化工学院,获理学博士学位
2004.9-2006.2 韩国科学技术研究院,博士后研究
2006.10-2008.8 韩国梨花女子大学,博士后研究
2008.12-至今 南京师范大学化学与材料科学学院工作,南京师范大学弘爱精英教师;生物医药功能材料国家地方联合工程研究中心暨江苏省生物医药功能材料协同创新中心主任;
国际学术期刊Oncology Research编委
近年来在Nature Nanotechnology、Nature Communications、Science Advances、Advanced Materials、Journal of the American Chemical Society、Angewandte Chemie International Edition等高水平期刊上发表学术论文180余篇;申请或授权国家发明专利20余件;制定团体标准1项;获得2009年度教育部高等学校科学研究优秀成果奖(自然科学)一等奖1项;2021年中国产学研合作创新成果奖一等奖1项;2022年江苏省科技进步二等奖1项;2023年江苏省高等学校科学研究成果奖三等奖1项;主持和参与国家自然科学基金项目和省部级科研项目10余项;企业横向项目3项;应世界著名科技出版社Wiley公司之邀,撰写生物医用微纳米机器人英文专业书籍“Biomedical Micro- and Nanorobots in Disease Treatment. Design, Preparation, and Applications”(2023年3月出版发行);组织主办多次国内外专业会议等。
研究方向(Research)
1. 生物医用材料及器械研发
2. 重大疾病诊疗用微纳米机器人创新药物(递送)体系
科研项目(Projects)
1. 国家自然科学基金:人工线粒体纳米马达体内“搭便车”实现心肌缺血再灌注损伤后内源性心肌修复的机制研究,2025
2. 国家自然科学基金:基于联合逐级靶向策略/级联效应的趋化性纳米马达用于脑瘤增强免疫治疗研究,2022
3. 南京市产业化重大项目,2021
4. 江苏省社会发展面上项目:基于纳米马达技术构建新型药物涂层球囊及其应用研究, 2019
5. 国家自然科学基金:医用金属表面原位构建药物/介孔分子筛复合体及其多功能性研究,2017
6. 江苏省重点研发计划(产业前瞻与共性关键技术):高分子复合材料多孔微结构人工髋关节微喷成形关键技术与装备研发,2016
7. 横向项目:负载白黎芦醇纳米制备技术,2014
8. 省自然科学基金项目:新型无多聚物药物涂层冠脉金属支架的制备及其生物相容性, 2012
9. 国家自然科学基金:冠脉支架表面聚乙二醇-磷铵两性离子复合物的化学修饰及其生 物相容性的基础研究,2011
近期代表成果(通讯联系人)(Publications)
1. Size-variable self-feedback nanomotors for glioblastoma therapy via mitochondrial mineralization. Nature Communications 2025, 16, 8990.
2. Chaperone nanomotors with chemotactic ability for the treatment of Parkinson’s disease. Science Advances 2025, 11, eadw1061.
3. Artificial mitochondrial nanorobots deliver energy in vivo by oral administration. Advanced Materials 2025, 202500495.
4. Oral mitochondrial transplantation using nanomotors to treat ischaemic heart disease. Nature Nanotechnology 2024, 19, 1236.
5. Enhancing exosomal delivery to abdominal aortic aneurysms using magnetically responsive chemotactic nanomotors for elastic matrix regenerative repair. Advanced Science 2024, 2405085.
6. Artificial neutrophils against vascular graft infection. Advanced Science 2024, 2402768.
7. Nanomotor-based H2S donor with mitochondrial targeting function for treatment of Parkinson's disease. Bioactive Materials, 2024, 31, 578-589.
8. A nitric-oxide driven chemotactic nanomotor for enhanced immunotherapy of glioblastoma. Nature Communications 2023, 14, 941.
9. Chemotactic NO/H2S nanomotors realizing cardiac targeting of G-CSF against myocardial ischemia-reperfusion injury. ACS Nano 2023, 17, 12573-12593.
10. Artificial cells: past, present and future. ACS Nano 2022, 16, 10, 15705-15733.
11. A universal chemotactic targeted delivery strategy for inflammatory diseases. Advanced Materials 2022, 202206654.
12. Three laws of design for biomedical micro/nanorobots. Nano Today 2022, 45, 101560.
13. Nitric oxide nanomotor driving exosomes-loaded microneedles for achilles tendinopathy healing. ACS Nano 2021, 15, 13339-13350.
14. Nanomotor-based adsorbent for blood Lead(II) removal in vitro and in pig models. Bioactive Materials 2021, 6, 1140-1149.
15. Biosafety, functionalities, and applications of biomedical micro/nanomotors. Angewandte Chemie International Edition 2021, 60, 13158-13176.
16. Nitric oxide-driven nanomotor for deep tissue penetration and multidrug resistance reversal in cancer therapy. Advanced Science 2021, 8, 2002525.
17. Systematic research and evaluation models of nanomotors for cancer combined therapy. Angewandte Chemie International Edition 2020, 59, 14458-14465.
18. Platelet-derived porous nanomotor for thrombus therapy. Science Advances 2020, 6, eaaz9014.
19. A safe and efficient strategy for the rapid elimination of blood lead in vivo based on a capture-fix-separate mechanism. Angewandte Chemie International Edition 2019, 58, 10582-10586.
20. Bio-inspired nitric-oxide-driven nanomotor. Nature Communications 2019, 10, 966.