姓名 ： 万密密
职称 ：教授
学位学历 :博士研究生，理学博士
邮箱： wanmimi@njnu.edu.cn
个人简介：
2015.07-至今 南京师范大学 博士后、讲师、副教授、教授（2024）
2010.09-2015.06 南京大学 博士 导师：朱建华教授
2006.09-2010.06 曲阜师范大学 学士
研究方向简介：
1.生物医用高分子纳米马达；
2.肿瘤、心血管疾病、神经退行疾病的治疗
主要科研项目（主持）：
国家自然科学基金优秀青年科学基金 2025-2027
国家自然科学基金面上项目 2023-2026
国家自然科学基金青年基金 2016-2019
中国博士后基金 2015-2017
江苏省博士后基金 2016-2017
南京师范大学高层次引进人才科研启动经费 2018-2021
南京师范大学中青年领军人才（青年拔尖人才），2021-2024
成果介绍：
自2012年以来，以第一作者或通讯作者身份发表50余篇学术论文，包括Nature Communications、Science Advances、Angewandte Chemie International Edition等国际期刊，授权发明专利5件。部分研究成果如下：
1. Wu Ziyu#, Chen Lin#, Guo Wenyan, Wang Jun, Ni Haiya, Liu Jianing, Jiang Wentao, Shen Jian, Mao Chun*, Zhou Min*, Wan Mimi*, Nat. Nanotechnol. 2024, doi:10.1038/s41565-024-01681-7.
2. Chen Huan, Li Ting, Liu Zhiyong, Tang Shuwan, Tong Jintao, Tao Yingfang, Zhao Zinan, Li Nan, Mao Chun*, Shen Jian, Wan Mimi*, A nitric-oxide driven chemotactic nanomotor for enhanced immunotherapy of glioblastoma. Nat. Commun. 2023, 14, 941.
3. Li Ting, Liu Zhiyong, Hu Jinglei, Chen Lin, Chen Tiantian, Tang Qianqian, Yu Bixia, Zhao Bo, Mao Chun*, Wan Mimi*, A Universal Chemotactic Targeted Delivery Strategy for Inflammatory Diseases. Adv. Mater. 2022, 34, 202206654.
4. Wang Qi, Li Ting, Yang Junying, Zhao Zinan, Tan Kaiyuan, Tang Shuwan, Wan Mimi*, Mao Chun*, Zhou Min*, Engineered Exosomes with Independent Module/Cascading Function for Therapy of Parkinson’s Disease by Multistep Targeting and Multistage Intervention Method. Adv. Mater. 2022, 34, 2201406.
5. Wu Ziyu, Zhou Min, Tang Xueting, Zeng Jiaqi, Li Yazhou, Sun Yuning, Huang Jia, Chen Lin, Wan Mimi*, Mao Chun, Carrier-Free Trehalose-Based Nanomotors Targeting Macrophages in Inflammatory Plaque for Treatment of Atherosclerosis. ACS Nano 2022, 16, 3808-3820.
6. Wan Mimi*, Liu Zhiyong, Li Ting, Chen Huan, Wang Qi, Chen Tiantian, Tao Yingfang, Mao Chun, Zwitterion-Based Hydrogen Sulfide Nanomotors Induce Multiple Acidosis in Tumor Cells by Destroying Tumor Metabolic Symbiosis. Angew. Chem. Int. Ed. 2021, 60, 16139-16148.
7. Chen Huan#, Shi Tao#, Wang Yue, Liu Zhiyong, Liu Fangcen, Zhang Huanyu, Wang Xingwen, Miao Zhuoyue, Liu Baorui, Wan Mimi*, Mao Chun, Wei Jia*, Deep penetration of nanolevel drugs and micrometer-level T cells promoted by nanomotors for cancer immunochemotherapy. J. Am. Chem. Soc. 2021, 143, 12025-12037.
8. Liu Anlong, Wang Qi, Zhao Zinan, Wu Rui, Wang Maochun, Li Jiawei, Sun Kuoyang, Sun Ziying, Lv Zhongyang, Xu Jia, Jiang Huiming, Wan Mimi*, Shi Dongquan*, Mao Chun*, Nitric oxide nanomotor driving exosomes-loaded microneedles for achilles tendinopathy healing. ACS Nano 2021, 15, 13339-13350.
9. Wan Mimi#, Chen Huan#, Wang Zhongda, Liu Zhiyong, Yu Yueqi, Li Ting, Miao Zhuoyue, Wang Xingwen, Wang Qi, Mao Chun*, Shen Jian*, Wei Jia*, Nitric oxide-driven nanomotor for deep tissue penetration and multidrug resistance reversal in cancer therapy. Adv. Sci. 2021, 8, 2002525.
10. Wan Mimi#*, Li Ting#, Chen Huan, Mao Chun*, Shen Jian*,Biosafety, functionalities and applications of biomedical micro/nanomotors. Angew. Chem. Int. Ed. 2021, 60, 2-21.
11. Wan Mimi#*, Wang Qi#, Wang Rongliang, Wu Rui, Li Ting, Fang Dan, Huang Yangyang, Yu Yueqi, Fang Leyi, Wang Xingwen, Zhang Yinghua, Miao Zhuoyue, Zhao Bo, Wang Fenghe, Mao Chun*, Jiang Qing, Xu Xingquan, Shi Dongquan*, Platelet-derived porous nanomotor for thrombus therapy. Sci. Adv. 2020, 6, eaaz9014.
12. Wan Mimi#, Wang Qi#, Li Xiaoyun, Xu Bo, Fang Dan, Li Ting, Yu Yueqi, Fang Leyi, Wang Yue, Wang Meng, Wang Fenghe, Mao Chun*, Shen Jian*, Wei Jia*, Systematic research and evaluation models of nanomotors for cancer combined therapy. Angew. Chem. Int. Ed.2020, 59, 14458-14465.
13. Wan Mimi#, Chen Huan, Wang Qi, Niu Qian, Xu Ping, Yu Yueqi, Zhu Tianyu, Mao Chun*, Shen Jian*, Bio-inspired nitric-oxide-driven nanomotor. Nat. Commun. 2019, 10(1), 966.
14. Wan Mimi, Xu Tingting, Chi Bo, Wang Meng, Huang Yangyang, Wang Qi, Li Ting, Yan Wenqiang, Chen Huan, Xu Ping, Mao Chun*, Zhao Bo, Shen Jian*, Xu Hong, Shi Dongquan*, A safe and efficient strategy for the rapid elimination of blood lead in vivo based on a capture–fix–separate mechanism. Angew. Chem. Int. Ed. 2019, 58, 10582-0586.
