
姓名:宋亮亮
职称:副教授
学位:博士
邮箱:liangliangsong@njnu.edu.cn
学习与工作经历:
2025.10-至今 南京师范大学 化学与材料科学学院 副教授
2021.01-2025.09 南京林业大学 化学工程学院 副教授
2019.09-2020.11 比利时鲁汶天主教大学 博士后 导师:Erik van der Eycken
2016.09-2019.08 比利时鲁汶天主教大学 博士 导师:Erik van der Eycken
2013.09-2016.06 厦门大学 硕士 导师:Eric Meggers教授、龚磊教授
2009.09-2013.06 合肥工业大学 本科
研究方向:
1. 过渡金属催化 2. 不对称合成
科研项目:
1. 国家自然科学基金青年项目(2025-2027)
2. 江苏省自然科学基金青年项目(2022-2025)
3. 江苏省高校基础研究面上项目(2022-2024)
荣誉与奖励:
1. 南京师范大学优秀高层次引进人才
2. 江苏省“双创”博士
发表论文(一作或通讯):
1. L. Song, L. Cai, L. Gong*, E. V. Van der Eycken*, Photoinduced copper-catalyzed enantioselective coupling reactions, Chem. Soc. Rev. 2023, 52, 2358-2376. (一区,IF 46.2)
2. X. Tang, E. V. Van der Eycken*, L. Song*, Photoinduced asymmetric alkylation of imines, Coord. Chem. Rev. 2026, 547, 217093 (一区,IF 23.5).
3. L. Song, L. Cai, E. V. Van der Eycken*, L. Gong*, Recent advances in copper-catalyzed multicomponent reactions with photoinduction, Coord. Chem. Rev. 2025, 528, 216428 (一区,IF 20.3).
4. P. Pei, M. Zhao, D. Lin, Z. Dong, L. Song*, L.-A. Chen*, Manganese-catalyzed redox-neutral thiolation of alkyl halides with thioformates, Angew. Chem. Int. Ed. 2023, e202305510.(一区,IF 16.8)
5. Z. Dong, Q. Tang, C. Xu, L. Chen, H. Ji, S. Zhou, L. Song*, L.-A. Chen*, Directed asymmetric nickel-catalyzed reductive 1, 2-diarylation of electronically unactivated alkenes, Angew. Chem. Int. Ed. 2023, 62, e202218286.(一区,IF 16.8)
6. M. Dai, J. Chang, Z. Sun, G. Wu, L. Song*, L.-A. Chen*, Palladium-Catalyzed Regio-, Chemo-, and Stereoselective Access to Multisubstituted 1,3-Dienes via Redox-Neutral Dienylation Pathway, CCS Chem. 2025, DOI: 10.31635/ccschem.025.202505704. (一区,IF 9.2)
7. Y. Guan, D. Lin, L. Song*, L.-A. Chen*, Nickel-Catalyzed C-H Arylation and Alkylation of Aldehydes Enabling Modular Chalcone Assembly, ACS Catal. 2025, 15, 14483-14492. (一区,IF 13.1)
8. L. Song*, Z. Zhang, Z. Lv, J. Xu, M. Zhan, S. Tang, H. Li, N. Wang*, L. Cai*, In situ generation of fluorescent amino acids and peptides via double C-H activation/annulation, ACS Catal. 2023, 13, 13569-13576.(一区,IF 12.9)
9. Z. Li†, L. Song†(共一), L. Van Meervelt, G. Tian*, E. V. Van der Eycken*, Cationic gold(I)-catalyzed cascade bicyclizations for divergent synthesis of (spiro)polyheterocycles, ACS Catal. 2018, 8, 6388-6393.(一区,IF 11.4)
10. M. Dai, L. Song*, L.-A. Chen*, Stereoselective synthesis of substituted 1,3-dienes from propargylic esters: electrophilic-metal or redox catalysis? Sci. China Chem. 2024, 67, 1384-1396.(一区,IF 10.4)
11. C. Liu, L. Song*, V. A. Peshkov, E. V. Van der Eycken*, Transition metal-free selective C–S bond cleavage of Ugi-adducts for rapid preparation of peptidomimetics, Green Chem. 2022, 24, 2783-2787.(一区,IF 11.0)
12. Y. Xie, L. Huang, Y. Qi, J. Hu, L. Song*, H. Feng*, A highly efficient metal-free hydrocarbonylation of alkynes with propargylamines and water, Green Chem. 2022, 24, 1978-1982.(一区,IF 11.0)
13. L. Song, X. Zhang, X. Tang, L. Van Meervelt, J. Van der Eycken, J. N. Harvey*, E. V. Van der Eycken*, Ruthenium-catalyzed cascade C-H activation/annulation of N-alkoxybenzamides: reaction development and mechanistic insight, Chem. Sci. 2020, 11, 11562-11569.(一区,IF 9.3)
14. X. Tang, E. V. Van der Eycken*, L. Song*, Transition metal-catalyzed C-H activation/annulation for the construction of unnatural amino acids and peptides, Chin. Chem. Lett. 2025, DOI: 10.1016/j.cclet.2025.111678.(一区,IF 8.9)
15. Q. Quan, Y. Li, Z. Zhang, E. V. Van der Eycken*, L. Cai*, L. Song*, Rh(III)-Catalyzed Double C-H Activation toward Peptide-Benzazepine Conjugates, Org. Lett. 2025, 27, 482-487.(一区,IF 4.9)
16. Z. Zhang, T. Wan, Q. Quan, Y. Zang, J. Xu, S. Tang, N. Wang*, L. Cai*, L. Song*, Triple C-H Activation/Annulation: In Situ Construction of Fluorescent Peptides, Org. Lett. 2024, 26, 10915-10920.(一区,IF 4.9)
17. L. Song*, Z. Lv, Y. Li, K. Zhang, E. V. Van der Eycken*, L. Cai*, Construction of peptide-isoquinolone conjugates via Rh(III)-catalyzed C-H activation/annulation, Org. Lett. 2023, 25, 2996-3000.(一区,IF 6.1)
18. C. Liu, A. Bolognani, L. Song*, L. Van Meervelt, V. A. Peshkov, E. V. Van der Eycken*, Gold(I)-catalyzed intramolecular bicyclization: divergent construction of quinazolinone and ampakine analogues, Org. Lett. 2022, 24, 8536-8541.(一区,IF 6.1)
19. C. Liu, L. Song*, L. Van Meervelt, V. A. Peshkov, Z. Li*, E. V. Van der Eycken*, Palladium-catalyzed arylative dearomatization and subsequent aromatization/dearomatization/aza-Michael addition: access to Zephycarinatine and Zephygranditine skeletons, Org. Lett. 2021, 23, 5065-5070.(一区,IF 6.0)
20. L. Song, G. Tian*, L. Van Meervelt, E. V. Van der Eycken*, Synthesis of pyrrolo[1,2-b]isoquinolines via gold(I)-catalyzed cyclization/enyne cycloisomerization/1,2-migration cascade, Org. Lett. 2020, 22, 6537-6542.(一区,IF 6.1)
21. H. Tang, M. Dai, D. Zhou, L. Song*, L.-A. Chen*, Transition metal-catalyzed redox-neutral 1,3-dienylation of propargylic esters and divergent synthesis, Org. Chem. Front. 2024, 11, 6231-6242.(一区,IF 4.6)
22. X. Tang, Q. Tao, L. Song*, E. V. Van der Eycken*, Recent advances in post Ugi-4CR dearomatizations for constructing spiro heterocycles, Org. Chem. Front. 2024, 11, 4895-4912.(一区,IF 4.6)
23. C. Xu, J. Chang, Z. Dong, L. Song*, L.-A. Chen*, Direct and modular access to allylic amines via nickel-catalyzed three-component coupling, Org. Chem. Front. 2023, 10, 5592-5600.(一区,IF 5.4)
24. Z. Lv, Y. Li, E. V. Van der Eycken*, L. Cai*, L. Song*, 6-Exo-dig cyclization/dearomatization cascade towards N-O fused spiro polyheterocycles, Org. Chem. Front. 2023, 10, 4912-4917.(一区,IF 5.4)
25. C. Liu, L. Song*, V. A. Peshkov, E. V. Van der Eycken*, Facile construction of peptidomimetics by sequential C-S/C-N bond activation of Ugi-adducts, Org. Chem. Front. 2021, 8, 6968-6973.(一区,IF 5.3)
26. X. Tang, E. V. Van der Eycken*, L. Song*, Functionalization of amino acids and peptides via rhodium-catalyzed C–H activation, Chem. Commun. 2025, 61, 11746-11757.(二区,IF 4.2)
27. L. Song, G. Tian*, Y. He, E. V. Van der Eycken*, Rhodium(III)-catalyzed intramolecular annulation through C-H activation: concise synthesis of rosettacin and oxypalmatime, Chem. Commun. 2017, 53, 12394-12397.(一区,IF 6.3)
28. L. Song, L. Gong*, E. Meggers*, Asymmetric dual catalysis via fragmentation of a single rhodium precursor complex, Chem. Commun. 2016, 52, 7699-7702.(一区,IF 6.6)
29. L. Song, E. V. Van der Eycken*, Transition metal-catalyzed intermolecular cascade C-H activation/annulation processes for the synthesis of polycycles, Chem. Eur. J. 2021, 27, 121-144.(二区,IF 5.2)
30. L. Song, G. Tian, E. V. Van der Eycken*, Chemo- and regioselective catalyst-controlled carbocyclization of alkynyl ketones: rapid synthesis of 1-indanones and 1-naphthols, Chem. Eur. J. 2019, 25, 7645-7648.(二区,IF 5.2)
31. X. Tang, Y. Jiang, L. Song*, E. V. Van der Eycken*, Metal nanoparticle-catalyzed alkyne cyclization for the synthesis of heterocycles. Adv. Synth. Catal. 2024, 366, 3085-3104.(二区,IF 4.4)
32. L. Song, G. M. Ojeda-Carralero, D. Parmar, D. A. González-Martínez, L. Van Meervelt, J. Van der Eycken, J. Goeman, D. G. Rivera, E. V. Van der Eycken*, Chemoselective peptide backbone diversification and bioorthogonal ligation by ruthenium-catalyzed C-H activation/annulation. Adv. Synth. Catal. 2021, 363, 3297-3304.(二区,IF 5.8)
33. L. Song, G. Tian*, A. Blanpain, L. Van Meervelt, E. V. Van der Eycken*, Diversification of peptidomimetics and oligopeptides through microwave-assisted rhodium(III)-catalyzed intramolecular annulation, Adv. Synth. Catal. 2019, 361, 4442-4447.(二区,IF 5.5)
34. L. Song, S. Claessen, E. V. Van der Eycken*, Pyridine-enabled C-N bond activation for the rapid construction of amides and 4-pyridylglyoxamides by cooperative palladium/copper catalysis, J. Org. Chem. 2020, 85, 8045-8054.(二区,IF 4.3)
35. Y. He†, L. Song†(共一), C. Liu, D. Wu, Z. Li*, L. Van Meervelt, E. V. Van der Eycken*, Access to polycyclic azepino[5,4,3-cd]indoles via a gold-catalyzed post-Ugi dearomatization cascade, J. Org. Chem. 2020, 85, 15092-15103.(二区,IF 4.3)
36. X. Tang, L. Song*, E. V. Van der Eycken*, Post-Ugi cyclizations towards polycyclic N-heterocycles, Chem. Rec. 2023, e202300095.(二区,IF 6.9)
37. X. Tang, S. Ding, L. Song*, E. V. Van der Eycken*, Transition metal-catalyzed C-H activation/annulation approaches to isoindolo[2,1-b]isoquinolin-5(7H)-ones, Chem. Rec. 2023, 23, e202200255.(二区,IF 6.9)
38. X. Tang, Y. Jiang, L. Song*, E. V. Van der Eycken*, Recent advances in the synthesis of rosettacin, Molecules 2024, 29, 2176.(二区,IF 4.2)
39. L. Song*, L. Cai, E. V. Van der Eycken*, Microwave-assisted post-Ugi reactions for the synthesis of polycycles, Molecules 2022, 27, 3105.(二区,IF 4.9)
40. L. Song, C. Chao, G. Tian*, L. Van Meervelt, J. Van der Eycken, E. V. Van der Eycken*, Late-stage diversification of peptidomimetics and oligopeptides via gold-catalyzed post-Ugi cyclization, Mol. Catal. 2022, 522, 112240.(二区,IF 5.1)
41. C. Liu, L. Song*, L. Van Meervelt, E. V. Van der Eycken*. Rapid construction of C4-substituted phenanthridinones through palladium-catalyzed domino N-arylation/aryl-aryl coupling process. Mol. Catal. 2021, 513, 111766.(二区,IF 5.1)
42. L. Song, X. Zhang, G. Tian*, K. Robeyns, L. Van Meervelt, J. N. Harvey*, E. V. Van der Eycken*, Intramolecular cascade annulation triggered by C-H activation via rhodium hydride intermediate, Mol. Catal. 2019, 463, 30-36.(二区,IF 5.1)
43. L. Song, G. Tian, E. V. Van der Eycken*, Rhodium(III)-catalyzed intermolecular cascade annulation through C-H activation: concise synthesis of rosettacin, Mol. Catal. 2018, 459, 129-134.(二区,IF 5.1)
44. L. Song, R. Manno, P. Ranjan, V. Sebastian,* S. Irusta, R. Mallada, L. Van Meervelt, J. Santamaria, E. V. Van der Eycken*, Preparation of Cu cluster catalysts by simultaneous cooling-microwave heating: application in radical cascade annulation, Nanoscale Adv. 2021, 3, 1087-1095.(二区,IF 4.3)
45. M. Dai, L. Kabandula, L. Tai, B. Wu, L. Song*, L.-A. Chen*, Transition metal-catalyzed synthesis of 1,2,3,4-tetrasubstituted 1,3-dienes from propargylic esters, ChemCatChem 2024, 16, e202301738.(三区,IF 3.8)
46. Z. Dong, L. Song*, L.-A. Chen*, Enantioselective Ni-catalyzed three-component dicarbofunctionalization of alkenes, ChemCatChem 2023, 15, e202300803.(三区,IF 4.5)
47. Z. Zhang, L. Cai*, L. Song*, Peptide diversification through addition reaction of free carboxylic acids to ynamides, Processes 2023, 11, 2262.(三区,IF 3.5)
48. X. Tang, L. Song*, Recent access to polycycles via post-Ugi reactions, Processes 2023, 11, 699.(三区,IF 3.5)
49. Z. Lv, Y. Li, L. Cai*, L. Song*, Metal-free bicyclization for the construction of N-O fused tetracyclic isoquinolones, Asian J. Org. Chem. 2023, 12, e202300393.(三区,IF 2.8)
50. Y. Chen, D. Lin, Z. Yu, Z. Dong, L. Song*, L.-A. Chen*, LiBr-mediated cross-coupling towards α-trifluoromethylamines, Asian J. Org. Chem. 2023, 12, e202300352.(三区,IF 2.8)
51. L. Song*, Z. Lv, K. Zhang, Y. Wu, E. V. Van der Eycken, L. Cai*, Recent advances in the asymmetric total synthesis of camptothecin, Asian J. Org. Chem. 2022, 11, e202200515.(三区,IF 3.1)
52. C. Liu, R. Zhao, L. Song*, Z. Li, G. Tian, Y. He, L. Van Meervelt, V. A. Peshkov, E. V. Van der Eycken*. Palladium-catalyzed post-Ugi arylative dearomatization/Michael addition cascade towards plicamine analogues. Org. Biomol. Chem. 2021, 19, 9752-9757.(三区,IF 3.9)
53. L. Song, G. Tian, J. Van der Eycken, E. V. Van der Eycken*, Intramolecular cascade annulation triggered by rhodium(III)-catalyzed sequential C(sp2)-H activation and C(sp3)-H amination, Beilstein J. Org. Chem. 2019, 15, 571-576.(三区,IF 2.6)