姓 名：刘平生
职 称：教授
学位学历：博士研究生，理学博士
联系电话：025-85891536
E-mail：liups@njnu.edu.cn
个人简介：
刘平生，2010年6月毕业于南京大学化学化工学院（高分子化学与物理专业），获理学博士学位；2010年9月至2014年7月在美国麻省大学医学院从事博士后研究；2014年8月以高层次人才被引进到南京师范大学化学与材料科学学院材料系工作。现为南京师范大学化学与材料科学学院教授，博士生导师；江苏省生物医用功能材料协同创新中心副主任，中国复合材料学会生物医用复合材料分会秘书长，江苏省生物医学工程学会常务理事，江苏省生物医学工程学会生物材料专业委员会主任委员，中国生物材料学会第一届监事会秘书。
研究方向
l 生物医用材料表面多功能涂层材料
l 组织粘合剂/生物胶水材料
l 骨、皮肤组织修复材料
l 光动力抗菌材料
主持科研项目
1、 常州市“揭榜挂帅”科技攻关重点项目 （320万）
2、 国家自然科学基金青年项目（21504046，24.7万）
3、 江苏省自然科学基金青年项目（BK20150970，20万）
4、 江苏省高校自然科学研究项目（15KJB430020，3万）
5、 功能聚合物的开发（横向， 76万）
6、 电池隔膜特种聚合物胶黏剂的开发（横向，15万）
7、 江苏省生物医药功能材料协同创新中心重点项目
8、 南京师范大学青蓝工程学术带头人
9、 南京师范大学高层次人才启动经费
奖励及荣誉
2022年12月，荣获江苏省科技进步二等奖（排名4/10）
2022年7月，南京市优秀专利奖（优秀发明专利）
2020年1月 中国产学研合作创新成果一等奖（项目名称：基于表面两性离子构建的材料生物相容性关键技术及应用，排名4/10）
2018年7月，江苏省“六大人才高峰”高层次人才
2017年6月，南京师范大学青蓝工程学术带头人
教学
承担本科生《高分子化学》、《高分子材料科学与工程》、《有机化学实验》、《大学化学实验》、《化学信息与科技文献》以及研究生《组织工程导论》、《现代化学进展-骨组织工程》等课程的教学。
主要研究成果
论文：
1. Peng, W.; Liu, C.; Lai, Y.; Wang, Y.; Liu, P.*; Shen, J.*, An Adhesive/Anti-Adhesive Janus Tissue Patch for Efficient Closure of Bleeding Tissue with Inhibited Postoperative Adhesion. Adv. Sci. 2023, 10, (21) 2301427.
2. Liu, P.; Sun, J.; Peng, W.; Gu, Y.; Ji, X.; Su, Z.; Liu, P.*; Shen, J., Zwitterionic betaines over HEPES as the new generation biocompatible pH buffers for cell culture. Bioact. Mater. 2023, 24, 376-386.
3. Dong, Y.; Li, Y.; Fan, B.; Peng, W.; Qian, W.; Ji, X.; Gan, D.*; Liu, P.*, Long-term antibacterial, antioxidative, and bioadhesive hydrogel wound dressing for infected wound healing applications. Biomater. Sci. 2023, 11, (6), 2080-2090.
4. Fan, B.; Peng, W.; Zhang, Y.; Liu, P.*; Shen, J.*, ROS conversion promotes the bactericidal efficiency of Eosin Y based photodynamic therapy. Biomater. Sci. 2023, 11, (14), 4930-4937.
5. Li, Y.; Peng, W.; Dong, Y.; Fan, B.; Qian, W.; Ji, X.; Lu, X.; Gan, D.*; Liu, P.*, Mussel-Inspired PEDOT-Incorporated Gelatin-Based Conductive Hydrogel with Flexibility and Electroactivity to Accelerate Wound Healing In Vitro. ACS Appl. Polym. Mater. 2023, 5, (6), 4233-4243.
6. Sun, J.; Peng, W.; Fan, B.; Gan, D.; Li, L.; Liu, P.*; Shen, J., Tertiary amines convert 1O2 to H2O2 with enhanced photodynamic antibacterial efficiency. J. Hazardous Mater. 2022, 435.
7. Peng, W.; Fan, B.; Li, Y.; Dong, Y.; Qian, W.; Ji, X.; Gan, D.; Liu, P.*; Shen, J*., Layer-by-layer construction of zwitterionic/biguanide polymers on silicone rubber as an antifouling and bactericidal coating. J. Mater. Chem. B 2022, 10, (39), 8013-8023.
8. Ma, Z.; Sun, J.; Dong, X.; Gan, D.; Peng, W.; Li, Y.; Qian, W.; Liu, P.*; Shen, J.*, Zwitterionic/active ester block polymers as multifunctional coatings for polyurethane-based substrates. J. Mater. Chem. B 2022, 10, (19), 3687-3695.
9. Dong, X.; Peng, W.; Sun, J.; Li, Y.; Fan, B.; Dong, Y.; Gan, D.; Zhang, W.; Liu, P. *; Shen, J. *, Zwitterionic/phosphonate copolymer coatings endow excellent antifouling properties and robust re-mineralization ability of dentine substrates. J. Mater. Chem. B 2022, 10, (31), 5976-5988.
10. Liu, P.; Bao, T.; Sun, L.; Wang, Z.; Sun, J.; Peng, W.; Gan, D.; Yin, G.; Liu, P. *; Zhang, W. B. *; Shen, J. *, In situ mineralized PLGA/zwitterionic hydrogel composite scaffold enables high-efficiency rhBMP-2 release for critical-sized bone healing. Biomater. Sci. 2022, 10 (3), 781-793.
11. Gu, Y. ; Liu, H. ; Dong, X.; Ma, Z.; Li, Y.; Li, L.; Gan, D.; Liu, P. *; Shen, J. *, Zwitterionic-phosphonate block polymer as anti-fouling coating for biomedical metals. Rare Metals 2022, 41 (2), 700-712.
12. Peng, W.; Yin, H.; Liu, P.; Peng, J.; Sun, J.; Zhang, X.; Gu, Y.; Dong, X.; Ma, Z.; Shen, J. *; Liu, P. *, Covalently construction of poly(hexamethylene biguanide) as high-efficiency antibacterial coating for silicone rubber. Chem. Eng. J. 2021, 412, 128707.
13. Peng, J.; Liu, P.; Peng, W.; Sun, J.; Dong, X.; Ma, Z.; Gan, D.; Liu, P. *; Shen, J. *, Poly(hexamethylene biguanide) (PHMB) as high-efficiency antibacterial coating for titanium substrates. J. Hazardous Mater. 2021, 411, 125110.
14. Liu, L.; Peng, W.; Zhang, X.; Peng, J.; Liu, P. *; Shen, J. *, Rational design of phosphonate/quaternary amine block polymer as an high-efficiency antibacterial coating for metallic substrates. J. Mater. Sci. Technol. 2021, 62, 96-106.
15. Zhang, X.; Liu, L.; Peng, W.; Dong, X.; Gu, Y.; Ma, Z.; Gan, D.*; Liu, P. *, Phosphonate/zwitterionic/cationic terpolymers as high-efficiency bactericidal and antifouling coatings for metallic substrates. J. Mater. Chem. B 2021, 9 (20), 4169-4177.
16. Dong, Y.; Liu, L.; Sun, J.; Peng, W.; Dong, X.; Gu, Y.; Ma, Z.; Gan, D.; Liu, P. *, Phosphonate/quaternary ammonium copolymers as high-efficiency antibacterial coating for metallic substrates. J. Mater. Chem. B 2021, 9 (39), 8321-8329
17. Peng, W.; Liu, P.; Zhang, X.; Peng, J.; Gu, Y.; Dong, X.; Ma, Z.; Liu, P. *; Shen, J. *, Multi-functional zwitterionic coating for silicone-based biomedical devices. Chem. Eng. J. 2020, 398, 125663.
18. Liu, P.; Sun, L.; Wang, Z.; Sun, J.; Dong, Y.; Cao, L.; Shen, J.; Zhang, W. B. *; Liu, P. *, Biodegradable Zwitterion/PLGA Scaffold Enables Robust Healing of Rat Calvarial Defects with Ultralow Dose of rhBMP-2. Biomacromolecules 2020, 21 (7), 2844-2855.
19. Liu, H. W.; Liu, L.; Jiang, X. F.; Fan, J.; Peng, W.; Liu, P. M.; Yang, T.; Chen, H. L.; Jiang, W.; Yin, G. Y.; Liu, P.*; Shen, J.*, Rational design of a zwitterionic-phosphonic copolymer for the surface antifouling modification of multiple biomedical metals. J. Mater. Chem. B 2019, 7 (25), 4055-4065.
20. Liu, P. M.; Sun, L.; Liu, P. Y.; Yu, W. Q.; Zhang, Q. H.; Zhang, W. B.; Ma, J.; Liu, P.*; Shen, J. *, Surface modification of porous PLGA scaffolds with plasma for preventing dimensional shrinkage and promoting scaffold-cell/tissue interactions. J. Mater. Chem. B 2018, 6 (46), 7605-7613. （inside cover)
21. Huang, T.; Liu, H.; Liu, P.;* Liu, P.; Li, L.;* Shen, J., Zwitterionic copolymers bearing phosphonate or phosphonic motifs as novel metal-anchorable anti-fouling coatings. J. Mater. Chem. B 2017, 5, 5380 - 5389.
22. Liu, P.; Huang, T.; Liu, P.;* Shi, S.; Chen, Q.; Li, L.; Shen, J.,* Zwitterionic modification of polyurethane membranes for enhancing the anti-fouling property. J. Colloid. Interface Sci. 2016; 480:91-101.
23. Liu, P.; Song, J., Well-controlled ATRP of 2-(2-(2-azidoethyoxy)ethoxy)ethyl methacrylate for high-density click functionalization of polymers and metallic substrates. J. Polym. Sci. Part A-Polym. Chem. 2016; 54:1268-77.
24. Liu, P.; Skelly, J. D.; Song, J., Three-dimensionally presented anti-fouling zwitterionic motifs sequester and enable high-efficiency delivery of therapeutic proteins. Acta Biomater. 2014, 10, 4296-303.
25. Liu, P.; Domingue, E.; Ayers, D. C.; Song, J., Modification of ti6Al4V substrates with well-defined zwitterionic polysulfobetaine brushes for improved surface mineralization. ACS Appl. Mater. Inter. 2014, 6:7141-52.
26. Liu, P.; Emmons, E.; Song, J., A comparative study of zwitterionic ligands-mediated mineralization and the potential of mineralized zwitterionic matrices for bone tissue engineering. J. Mater. Chem. B 2014, 2, 7524-33.
27. Liu, P.; Chen, Q.; Li, L.; Lin, S.; Shen, J., Anti-biofouling ability and cytocompatibility of the zwitterionic brushes-modified cellulose membrane. J. Mater. Chem. B 2014, 2, 7222-7231.
28. Liu, P.; Song, J., Sulfobetaine as a zwitterionic mediator for 3D hydroxyapatite mineralization. Biomaterials 2013, 34, 2442-54.
29. Liu, P.; Smits, J.; Ayers, D. C.; Song, J., Surface mineralization of Ti6Al4V substrates with calcium apatites for the retention and local delivery of recombinant human bone morphogenetic protein-2. Acta Biomater. 2011, 7, 3488-95.
30. Liu, P.; Chen, Q.; Yuan, B.; Chen, M.; Wu, S.; Lin, S.; Shen, J., Facile surface modification of silicone rubber with zwitterionic polymers for improving blood compatibility. Mater. Sci. Eng. C, 2013, 33, 3865-74.
31. Liu, P.; Chen, Q.; Wu, S.; Shen, J.; Lin, S., Surface modification of cellulose membranes with zwitterionic polymers for resistance to protein adsorption and platelet adhesion. J. Membrane Sci. 2010, 350, 387-94.
32. Liu, P.; Chen, Q.; Liu, X.; Yuan, B.; Wu, S.; Shen, J.; Lin, S., Grafting of Zwitterion from Cellulose Membranes via ATRP for Improving Blood Compatibility. Biomacromolecules 2009, 10, 2809-16.
33. Liu, P.; Li, L.; Zhou, N.; Zhang, J.; Wei, S.; Shen, J., Synthesis and properties of a poly(acrylic acid)/montmorillonite superabsorbent nanocomposite. J. Appl. Polym. Sci. 2006, 102, 5725-5730.
34. Liu, P.; Li, L.; Zhou, N.; Zhang, J.; Wei, S.; Shen, J., Waste polystyrene foam-graft-acrylic acid/montmorillonite superabsorbent nanocomposite. J. Appl. Polym. Sci. 2007, 104, 2341-2349.
35. Yuan, B.; Chen, Q.; Ding, W.; Liu, P.; Wu, S.; Lin, S.; Shen, J.; Gai, Y., Copolymer coatings consisting of 2-methacryloyloxyethyl phosphorylcholine and 3-methacryloxypropyl trimethoxysilane via ATRP to improve cellulose biocompatibility. ACS Appl. Mater. Inter. 2012, 4, 4031-9.
36. Youssefian, S.; Liu, P.; Askarinejad, S.; Shalchy, F.; Song, J.; Rahbar, N., Experimental and numerical measurements of adhesion energies between PHEMA and PGLYMA with hydroxyapatite crystal. Bioinspir. Biomim. 2015, 10:046011.
37. Chen, H.; Zhu, H.; Liu, P.; Li, L., A study on the conformational space of the all-trans retinal deprotonated Schiff base. Comput. Theor. Chem. 2016, 1094, 1-7.
38. Ding, X.; Li, L.; Liu, P.; Zhang, J.; Zhou, N.; Lu, S.; Wei, S.; Shen, J., The preparation and properties of dextrin-graft-acrylic acid/montmorillonite superabsorbent nanocomposite. Polym. Composite. 2009,30:976-981.
