刘平

时间:2018-04-25 来源: 点击数:

15918

   姓名      刘平

   职称      副教授  

   学位学历  博士

   联系电话  15951988349

      E-mail     pingliu@njnu.edu.cn


个人简介:

2000.092004.07   东北师范大学,化学学院,获学士学位

2004.092007.07   华中师范大学,化学学院,获硕士学位

2007.082008.10   上海药明康德新药开发有限公司,FTE研究员

2009.092012.06   复旦大学,化学系,获博士学位

2012.072014.09  中国科学院上海有机化学研究所,助理研究员

2014.092017.09  南京师范大学,化学与材料科学学院,讲师

2017.09至今      南京师范大学,化学与材料科学学院,副教授

研究方向:

1. 有机合成新方法研究包括过渡金属催化串联反应构建“药学偏好”的杂环;可见光催化有机自由基反应;杂环化合物的C-H键官能团化反应等;

2. 药物分子合成工艺的优化。

在研项目:

1. 国家自然基金青年项目(21502097),主持,21万,2016.012018.12

2. 江苏省高校自然科学基金面上项目15KJB150015,主持,5万,2015.072017.06

成果介绍:

迄今已在J. Am. Chem. Soc.2篇)Chem. Commun.Org. Lett.J. Org. Chem.Org. Chem. Front.Org. Biomol. ChemEur. J. Org. Chem.Tetrahedron Lett.SynlettSCI期刊上发表论文27篇;

参写英文专著《Solvents as Reagents in Organic Synthesis》的第三章The Applications of 1,4-Dioxane, THF, and Ethers as Versatile Building Blocks in Organic Synthesis(Wiley出版社)

主讲课程:有机化学C,有机化学实验A

1. Qinfei Deng, Yan Xu, Ping Liu,* Liping Tan and Peipei Sun*, Photoredox-catalyzed cascade addition/cyclization of N-Propargyl aromatic amines: access to 3-difluoroacetylated or 3-fluoroacetylated quinolines, Org. Chem. Front., 2017, online (DOI: 10.1039/c7qo00714k).

2. Yulan Yu, Zhiqiang Cai, Weiwen Yuan, Ping Liu* and Peipei Sun*, Radical Addition/Insertion/Cyclization Cascade Reaction to Assemble Phenanthridines from N-Arylacrylamide Using Cyano as A Bridge under Photoredox Catalysis, J. Org. Chem. 2017, 82, 8148.

3. Qing Chang, Zhengyi Liu, Ping Liu,* Lu Yu and Peipei Sun*, Visible-Light-Induced Regioselective Cyanomethylation of Imidazopyridines and Its Application in Drug Synthesis, J. Org. Chem. 2017, 82, 5391. (Highlighted in Synfacts 2017, 13, 0784.)

4. Ping Liu, Guanghui Zhang and Peipei Sun*, Transition metal-free decarboxylative alkylation reactions, Org. Biomol. Chem. 2016, 14, 10763. (Invited review)

5. Ping Liu, Ziyan Shen, Yao Yuan and Peipei Sun*, Synthesis of symmetrical methylene-bridged imidazoheterocycles using DMSO as methylene source under metal-free conditions, Org. Biomol. Chem. 2016, 14, 6523.

6. Yongyuan Gao, Weiye Lu, Ping Liu* and Peipei Sun*, Iron-Catalyzed Regioselective Alkoxycarbonylation of Imidazoheterocycles with Carbazates, J. Org. Chem. 2016, 81, 2482.

7. Ping Liu, Yongyuan Gao, Weijin Gu, Ziyan Shen and Peipei Sun*, Regioselective Fluorination of Imidazo[1,2a]pyridines with Selectfluor in Aqueous Condition, J. Org. Chem. 2015, 80, 11559.

8. Yuki Fukui, Ping Liu (co-first author), Qiang Liu, Zhi-Tao He, Nuo-Yi Wu, Ping Tian* and Guo-Qiang Lin*, Tunable Arylative Cyclization of 1,6-Enynes Triggered by Rhodium(III)-Catalyzed C−H Activation, J. Am. Chem. Soc. 2014, 136, 15607.

9. Ping Liu, Yuki Fukui, Ping Tian,* Zhi-Tao He, Cai-Yun Sun, Nuo-Yi Wu and Guo-Qiang Lin*, Cu-Catalyzed Asymmetric Borylative Cyclization of Cyclohexadienone-Containing 1,6-Enynes, J. Am. Chem. Soc. 2013, 135, 11700. (Highlighted in Synfacts 2013, 9, 1209.)

10. Ping Liu, Qian-Qian Xu, Chao Dong, Xinsheng Lei* and Guo-Qiang Lin*, A Complementary Approach to 3,5-Substituted Pyrazoles with Tosylhydrazones and Terminal Alkynes Mediated by TfOH, Synlett 2012, 23, 2087.

11. Ping Liu, Chun-Lin Deng, Xinsheng Lei* and Guo-qiang Lin*, Tandem Amination/Cycloisomerization of Aryl Propargylic Alcohols with 2-Aminopyridines as an Expedient Route to imidazo[1,2-a]pyridines, Eur. J. Org. Chem. 2011, 7308. (Highlighted in Synfacts 2012, 8, 0134.)

12. Ping Liu, Li-song Fang, Xinsheng Lei* and Guo-qiang Lin*, Synthesis of imdazo[1,2a]pyridines via three-component reaction of 2-aminopyridines, aldehydes and alkynes, Tetrahedron Lett. 2010, 51, 4605.


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